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It had been shown that eicosapentaenoic acid variations the lipid composition in caveolae and induces eNOS translocation from caveolae to soluble fractions, which was accompanied by a stimulated ability to generate NO in cells (112). Consequently, docosahexaenoic acid improvements the microenvironment of caveolae don't just by altering the lipid composition in the membrane but in addition by transforming the distribution of essential structural proteins, which include caveolin-one, and also encourages eNOS displacement from caveolae (113).
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Associations with eicosapentaenoic acid to arachidonic acid ratio and mortality in hospitalized coronary heart failure people.
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